NAD+ WELLNESS GUIDE

What Is NAD+? NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell in your body. It plays a foundational role in energy production, DNA repair, and cell signaling — processes that are essential not just for performance, but for healthy aging at the cellular level. NAD+ levels naturally decline with age, beginning as early as our 30s and continuing throughout life. This decline has been linked to decreased energy, slower recovery, reduced cognitive sharpness, and accelerated aging. Supplementing or infusing NAD+ is one of the most studied approaches in longevity and functional wellness medicine. How It Works NAD+ is a critical molecule in the mitochondria - the energy-producing structures within your cells. Its core functions include: Energy metabolism (ATP production): NAD+ is essential to the cellular processes that convert nutrients into usable energy. Sirtuin activation: Sirtuins are proteins that regulate aging and stress response. NAD+ is required for their function, making it directly linked to longevity pathways. DNA repair: NAD+ fuels PARP enzymes that detect and repair damaged DNA - a key mechanism in cellular health and cancer prevention research. Circadian rhythm regulation: Emerging research suggests NAD+ plays a role in synchronizing the body's internal clock, influencing sleep quality and metabolic function. Benefits: Both research and clinical experience point to a compelling range of benefits from NAD+ therapy: Increased energy and reduced fatigue - often reported within the first few sessions Sharper mental clarity, focus, and cognitive performance Enhanced cellular repair and recovery, particularly valuable after illness, stress, or intensive training. Support for healthy aging by activating longevity-associated pathways Mood stabilization - NAD+ is a precursor to neurotransmitters including serotonin Metabolic support, including improved insulin sensitivity in some patients. Delivery Methods; NAD+ can be administered in several ways, each with distinct absorption profiles: IV Infusion: The gold standard for bioavailability. NAD+ is delivered directly into the bloodstream, bypassing digestion entirely. Sessions typically run 2–4 hours depending on dose. Intramuscular (IM) Injection: A faster, more convenient option that provides good absorption without the time commitment of an IV drip. Subcutaneous Injection: Self-administered between clinical visits to maintain consistent NAD+ levels. Oral Precursors (NMN/NR): Supplement forms that the body converts to NAD+. Lower bioavailability than injectable forms, but a practical adjunct to clinical therapy. What to Expect: NAD+ infusions have a distinctive experience: warmth, tingling, and a sense of energy during the drip are common. These sensations are normal and subside as the infusion rate is adjusted. Most patients feel a noticeable difference in energy and clarity within 24–48 hours of their first session. For optimal results, a loading protocol of multiple initial sessions is typically recommended, followed by maintenance infusions on a monthly or quarterly basis depending on your goals and baseline NAD+ status. Safety and Contraindications. NAD+ therapy has a strong safety profile and is generally very well tolerated. It is not recommended for individuals with active malignancy, as NAD+ is required for cellular growth and replication. Patients who are pregnant or breastfeeding should consult their provider before beginning treatment. At Showface, all NAD+ protocols begin with a health evaluation. Dosing, frequency, and delivery

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NAD+ WELLNESS GUIDE

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